EPA

recomandam intr-un post mai vechi EPA intr-un regim de slabire...un studiu nou pare sa confirme acest sfat

Genes Nutr. 2008 Feb;2(4):327-30.

Eicosapentaenoic acid increases lipolysis through up-regulation of the lipolytic gene expression and down-regulation of the adipogenic gene expression in 3T3-L1 adipocytes.

In this study, we investigated the lipolytic effects of eicosapentaenoic acid (EPA) in 3T3-L1 adipocytes. The differentiated 3T3-L1 adipocytes were treated in a serum-free medium with 300 muM of EPA for 3, 6, 12, and 24 h. In comparison with the control, intracellular lipid accumulation was significantly decreased by 24% at 24 h following the addition of EPA.These results imply that EPA attenuates lipid accumulation in adipocytes, possibly via down-regulation of PPAR-c andinduction of ACC gene expression. EPA may modulate lipid metabolism by stimulation of lipolysis, which was associated with induction of lipolytic gene expression and suppression of adipogenic gene expression in 3T3-L1 adipocytes.

PMID: 18850226 [PubMed - in process]